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Publication Information
Authors
Steubl Dominik, Buzkova Petra, Garimella Pranav S., Ix Joachim H., Devarajan Prasad, Bennett Michael R., Chaves Paolo H. M., Shlipak Michael G., Bansal Nisha, Sarnak Mark J.
Studies
Abstract
Uromodulin is released by tubular epithelial cells into the serum and lower levels are associated with more severe interstitial fibrosis and tubular atrophy (IF/TA). Low serum uromodulin (sUMOD) levels are associated with mortality and cardiovascular disease. However, little is known about the association of sUMOD with long-term kidney outcomes in older adults, a population with a high prevalence of IF/TA.