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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2021
Affiliation
Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, USA.; Gene Expression and RNA Metabolism Laboratory, Instituto de Biomedicina de Valencia (CSIC), Jaume Roig, 11, 46010, Valencia, Spain.; Laboratory of Neurobiology, Prince Felipe Research Center, Valencia, Spain.; Department of Pediatrics, University of Florida Diabetes Institute, Gainesville, FL, USA.; Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute, Gainesville, FL, USA.; Department of Pediatrics, University of Florida Diabetes Institute, Gainesville, FL, USA.; Department of Pediatrics, University of Florida Diabetes Institute, Gainesville, FL, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA.; Microbiology and Cell Science Department, Institute for Food and Agricultural Sciences, University of Florida, Gainesville, USA. aconesa@ufl.edu.
Authors
Balzano-Nogueira Leandro, Ramirez Ricardo, Zamkovaya Tatyana, Dailey Jordan, Ardissone Alexandria N, Chamala Srikar, Serrano-Quílez Joan, Rubio Teresa, Haller Michael J, Concannon Patrick, Atkinson Mark A, Schatz Desmond A, Triplett Eric W, Conesa Ana
Studies

Abstract

The Environmental Determinants of Diabetes in the Young (TEDDY) is a prospective birth cohort designed to study type 1 diabetes (T1D) by following children with high genetic risk. An integrative multi-omics approach was used to evaluate islet autoimmunity etiology, identify disease biomarkers, and understand progression over time.