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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2023
Affiliation
Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California, San Diego School of Medicine , San Diego , California , USA.; Center for Computational Biology and Bioinformatics , University of California, San Diego , La Jolla , California , USA.; Center for Computational Biology and Bioinformatics , University of California, San Diego , La Jolla , California , USA.; Department of Pathology, Sharp Memorial Hospital; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California , San Diego , California , USA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California, San Diego School of Medicine , San Diego , California , USA.; Department of Pediatrics , Feinberg Medical School of Northwestern University , Chicago , Illinois , USA.; Riley Hospital for Children At Indiana University Health , Indianapolis , Indiana , USA.; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics , St. Louis University , St. Louis , Missouri , USA.; Section of Pediatric Gastroenterology, Hepatology and Nutrition, Riley Hospital for Children , Indiana University School of Medicine, Indiana University , Indianapolis , Indiana , USA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California, San Diego School of Medicine , San Diego , California , USA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California, San Diego School of Medicine , San Diego , California , USA.; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Department of Pediatrics , University of Cincinnati College of Medicine , Cincinnati , Ohio , USA.; Department of Epidemiology and Biostatistics , Johns Hopkins University , Baltimore , Maryland , USA.; The Translational Genomics Research Institute (TGen) , Phoenix , Arizona , USA.; Center for Computational Biology and Bioinformatics , University of California, San Diego , La Jolla , California , USA.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics , University of California, San Diego School of Medicine , San Diego , California , USA.
Authors
Goyal Nidhi P, Rosenthal Sara B, Nasamran Chanod, Behling Cynthia A, Angeles Jorge E, Fishbein Mark H, Harlow Kathryn E, Jain Ajay K, Molleston Jean P, Newton Kimberly P, Ugalde-Nicalo Patricia, Xanthankos Stavra A, Yates Katherine, Schork Nicholas J, Fisch Kathleen M, Schwimmer Jeffrey B

Abstract

NAFLD is the most common chronic liver disease in children. Large pediatric studies identifying single nucleotide polymorphisms (SNPs) associated with risk and histologic severity of NAFLD are limited. Study aims included investigating SNPs associated with risk for NAFLD using family trios and association of candidate alleles with histologic severity.