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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2021
Affiliation
Section of Nephrology, Department of Medicine, Baylor University College of Medicine, Houston, TX; Section of Nephrology, Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX; Institute of Clinical and Translational Research, Baylor College of Medicine, Houston, TX. Electronic address: sankar.navaneethan@bcm.edu.; Integrated Physiology and Molecular Medicine, Pennington Biomedical Research Center, Baton Rouge, LA.; Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH.; Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH.; Canatomical Services, Toronto, Ontario, Canada.; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.; Department of Nephrology, MetroHealth Medical Center, Cleveland, OH.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.; Division of Nephrology, Department of Medicine, University of Illinois at Chicago College of Medicine, Chicago, IL.; Canatomical Services, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada.; Division of Nephrology and Hypertension, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH.; Division of Nephrology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI.; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; Center for Populations Health Research, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.; Department of Medicine, University of Mississippi Medical Center, Jackson, MS.; Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH.; Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.; Renal, Electrolyte, and Hypertension Division, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, MD.
Authors
Navaneethan Sankar D, Kirwan John P, Remer Erick M, Schneider Erika, Addeman Bryan, Arrigain Susana, Horwitz Ed, Fink Jeffrey C, Lash James P, McKenzie Charles A, Rahman Mahboob, Rao Panduranga S, Schold Jesse D, Shafi Tariq, Taliercio Jonathan J, Townsend Raymond R, Feldman Harold I
Studies

Abstract

Adiposity and physical fitness levels are major drivers of cardiometabolic risk, but these relationships have not been well-characterized in chronic kidney disease (CKD). We examined the associations of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intrahepatic fat, and physical function with inflammation, insulin resistance, and adipokine levels in patients with CKD.