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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2017
Authors
Pottel Hans, Dubourg Laurence, Schaeffner Elke, Eriksen Bjørn Odvar, Melsom Toralf, Lamb Edmund J., Rule Andrew D., Turner Stephen T., Glassock Richard J., De Souza Vandréa, Selistre Luciano, Goffin Karolien, Pauwels Steven, Mariat Christophe, Flamant Martin, Bevc Sebastjan, Delanaye Pierre, Ebert Natalie
Studies

Abstract

The data presented in this article are related to the research article entitled “The Diagnostic Value of Rescaled Renal Biomarkers Serum Creatinine and Serum Cystatin C and their Relation with Measured Glomerular Filtration Rate” (Pottel et al. (2017) [1]). Data are presented demonstrating the rationale for the normalization or rescaling of serum cystatin C, equivalent to the rescaling of serum creatinine. Rescaling biomarkers brings them to a notionally common scale with reference interval [0.67–1.33]. This article illustrates the correlation between rescaled biomarkers serum creatinine and serum cystatin C by plotting them in a 2-dimensional graph. The diagnostic value in terms of sensitivity and specificity with measured Glomerular Filtration Rate as the reference method is calculated per age-decade for both rescaled biomarkers. Finally, the interchangeability between detecting impaired kidney function from renal biomarkers and from the Full Age Spectrum FAS-estimating GFR-equation and measured GFR using a fixed and an age-dependent threshold is shown.