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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2019
Authors
Pike Mindy, Stewart Thomas G., Morse Jennifer, Ormsby Patrick, Siew Edward D., Hung Adriana, Abdel-Kader Khaled, Ikizler T. Alp, Lipworth Loren, Robinson-Cohen Cassianne
Studies

Abstract

High dietary acid load and metabolic acidosis are associated with an accelerated decline in kidney function and may contribute to the observed heterogeneity in end-stage renal disease (ESRD) risk according to APOL1 genotype. Our objective was to examine the associations of metabolic acidosis and dietary acid load with kidney disease progression, according to APOL1 genotype, among individuals with chronic kidney disease (CKD).