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Publication Information
Affiliation
Boston University School of Medicine, Boston, Massachusetts.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University, Baltimore, Maryland.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.
Authors
He William J, Li Changwei, Huang Zhijie, Geng Siyi, Rao Varun S, Kelly Tanika N, Hamm L Lee, Grams Morgan E, Arking Dan E, Appel Lawrence J, Rebholz Casey M
Studies
Abstract
Mitochondrial DNA copy number is a biomarker of mitochondrial function, which has been hypothesized to contribute to pathogenesis of CKD through podocyte injury, tubular epithelial cell damage, and endothelial dysfunction. The prospective association of mitochondrial DNA copy number with CKD progression has not been previously evaluated.