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Publication Information
Affiliation
Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.; Division of Renal Medicine, Brigham and women's Hospital, Boston, Massachusetts, USA.; Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.; Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.; Department of Medicine, Biological Sciences Department, University of Chicago, Chicago, Illinois, USA.; Department of Oncologic Neuroradiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.; Department of Nephrology, Cleveland Clinic, Cleveland, Ohio, USA.; Division of Nephrology, Department of Internal Medicine, Kansas University Medical Center, Kansas City, Kansas, USA.; Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, USA.; Division of Nephrology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.; Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.; Department of Medicine, Renal Division, Emory University School of Medicine, Atlanta, Georgia, USA.; National Institutes of Health (NIDDK), Bethesda, Maryland, USA.; Division of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.
Authors
Dad Taimur, Abebe Kaleab Z, Bae K Ty, Comer Diane, Torres Vicente E, Czarnecki Peter G, Schrier Robert W, Steinman Theodore I, Moore Charity G, Chapman Arlene B, Kaya Diana, Tao Cheng, Braun William E, Winklhofer Franz T, Brosnahan Godela, Hogan Marie C, Miskulin Dana C, Rahbari Oskoui Frederic, Flessner Michael F, Perrone Ronald D
Studies
Abstract
The high burden of cardiovascular morbidity and mortality in autosomal dominant polycystic kidney disease (ADPKD) is related to development of hypertension and left ventricular hypertrophy. Blood pressure reduction has been shown to reduce left ventricular mass in ADPKD; however, moderators and predictors of response to lower blood pressure are unknown.