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Publication Information

PubMed ID
Public Release Type
Journal
Publication Year
2016
Affiliation
Department of Oncology, Georgetown University, PS Room GD11, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Building D Suite 180 Room 185, 4000 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Basic Science Building D Room 255, 3900 Reservoir Rd NW, Washington, DC 20057 USA.; MedStar Georgetown University Transplant Institute, 2-PHC, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA USA.; Department of Oncology, Georgetown University, PS Room GD11, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.
Authors
Sanda Miloslav, Benicky Julius, Wu Jing, Wang Yiwen, Makambi Kepher, Ahn Jaeil, Smith Coleman I, Zhao Peng, Zhang Lihua, Goldman Radoslav
Studies

Abstract

Non-invasive monitoring of liver disease remains an important health issue. Liver secreted glycoproteins reflect pathophysiological states of the organ and represent a rational target for serologic monitoring. In this study, we describe sialylated O-glycoforms of liver-secreted hemopexin (HPX) and quantify them as a ratio of disialylated to monosialylated form (S-HPX).