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Publication Information
Affiliation
Section of Nephrology, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Renal Section, Evans Biomedical Research Center, 650 Albany Street, X504, Boston, MA 02118, USA.; Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and women's Hospital, Boston, MA 02115, USA.; Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.; Section of Nephrology, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Renal Section, Evans Biomedical Research Center, 650 Albany Street, X504, Boston, MA 02118, USA.
Authors
Verma Ashish, Vaidya Anand, Subudhi Sonu, Waikar Sushrut S
Studies
Abstract
Randomized controlled trials have demonstrated the efficacy of mineralocorticoid receptor (MR) antagonism in delaying chronic kidney disease (CKD) progression in diabetes; however, they have not investigated the role of aldosterone or whether these beneficial effects could be achieved in individuals without diabetes.