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Publication Information
Affiliation
Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Authors
Afdhal N, Agudelo E, Baker SM, Belle SH, Bilonick RA, Block G, Brown RS Jr, Brown S, Burton JR, Callison K, Cannon N, Cline J, Conjeevaram HS, Davis P, DeMedina M, Di Bisceglie A, Donlin M, Doo E, Dougherty K, Dove L, Everhart J, Ferris M, Fontana RJ, Fried MW, Geahigan T, Gibson K, Haritos M, Harsh D, Heberlein J, Hermitt C, Hinds M, Hoofnagle JH, Howell C, Howell CD, Im K, Jeffers LJ, Kelley S, Kelsey S, Klarquist J, Kleiner DE, Koozer L, Lawlor S, Lewis J, Liang TJ, Martin M, Ramcharran D, Rhodes SL, Robuck P, Rosen HR, Sanda C, Seeff LB, Shrestha R, Smith SR, Stovel S, Straley S, Su X, Tang G, Tang Y, Tavis JE, Taylor MW, Terrault N, Theodore D, Thomas SB, Tong X, Tsukahara T, Virahep-C Study Group, Wahed A, Wang D, Wang P, Wei Y, Weston S, Wiley TE, Williams M, Yang H, Yao E, Yee LJ, Zacks S, Zhang S
Studies
Citation
Su X, Yee LJ, Im K, Rhodes SL, Tang Y, Tong X, Howell C, Ramcharran D, Rosen HR, Taylor MW, Liang TJ, Yang H, Virahep-C Study Group. Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the response to interferon therapy for chronic hepatitis C. J Hepatol 2008 Aug;49(2):184-91. Epub 2008 May 20.Abstract
Interferon signaling pathway genes (IPGs) and interferon-stimulated genes (ISGs) are associated with the host response to hepatitis C virus (HCV) infection. We studied single nucleotide polymorphisms (SNPs) in IPGs and ISGs for their associations with response to pegylated interferon alpha-2a (Peg-IFN-alpha) plus ribavirin therapy in HCV genotype-1 infected patients.