NIDDK Central Repository - Plasma levels of growth-related oncogene (CXCL1-3) associated with fibrosis and platelet counts in HCV-infected patients.

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NIDDK Central Repository

Publication Information

DOI

10.1111/apt.13389

PubMed ID

26314558

Public Release Type

Journal

Publication Year

2015

Affiliation

Janssen Research and Development, Beerse, Belgium.

Authors

Aerssens J, Darling JM, Fanning G, Fried MW, Johansson S, Scholliers A, Talloen W, Tuefferd M

Studies

Virahep-C

Citation

Johansson S, Talloen W, Tuefferd M, Darling JM, Scholliers A, Fanning G, Fried MW, Aerssens J. Plasma levels of growth-related oncogene (CXCL1-3) associated with fibrosis and platelet counts in HCV-infected patients. Aliment Pharmacol Ther 2015 Nov;42(9):1111-21. Epub 2015 Aug 28.

Abstract

Fibrosis progression in hepatitis C virus (HCV)-infected patients varies greatly between individuals. Chemokines recruit immune cells to the infected liver and may thus play a role in the fibrosis process.